CD4+ T follicular helper (Tfh) cells in human tonsil and blood are clonally convergent, but divergent from non-Tfh CD4+ cells
E. Brenna, A. N. Davydov, K. Ladell, J. E. McLaren, P. Bonaiuti, M. Metsger, S. C. Gilbert, T. Lambe, D. A. Price, S. L. Campion, D. M. Chudakov, P. Borrow, A. J. McMichael
The paper examines clonal relationships between Tfh cells in blood and tonsil, finding clonal convergence between peripheral and tonsillar Tfh cells but divergence from non-Tfh CD4+ cells.
bioRxiv · Aug 22, 2019Immunology