Dynamic coordination of the lever-arm swing of human myosin II in thick filaments on actin
H. Fukunaga, T. Washio, K. Fujita, M. Ohmachi, H. Takagi, K. Ikezaki, T. Yanagida, M. Iwaki
This study uses high-speed atomic force microscopy to observe myosin II lever-arm coordination in synthetic thick filaments, revealing how structural mismatches enhance contraction efficiency.
bioRxiv · Aug 30, 2023 · PreprintBiophysics