Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors
A. J. Patel, Y.-W. Wan, R. Al-Ouran, J.-P. Revelli, M. F. Cardenas, M. Oneissi, L. Xi, A. Jalali, J. Magnotti, D. M. Muzny, H. Doddapaneni, S. Sebastian, K. A. Heck, J. C. Goodman, S. P. Gopinath, , T. J. Klisch
This study identifies three molecular types of meningiomas that better predict recurrence than WHO grading and links aggressive tumors to loss of DREAM complex repression.
bioRxiv · Sep 10, 2019Cancer Biology