Author

D. A. Wheeler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Boot· 1 shared A. J. Patel· 1 shared A. Jalali· 1 shared A. W. T. Ng· 1 shared D. A. Gordenin· 1 shared D. M. Muzny· 1 shared D. Yoshor· 1 shared E. Bergstrom· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Boot

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Author profile →

2 papers

Recent·Most cited

Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors

A. J. Patel, Y.-W. Wan, R. Al-Ouran, J.-P. Revelli, M. F. Cardenas, M. Oneissi, L. Xi, A. Jalali, J. Magnotti, D. M. Muzny, H. Doddapaneni, S. Sebastian, K. A. Heck, J. C. Goodman, S. P. Gopinath, , T. J. Klisch

This study identifies three molecular types of meningiomas that better predict recurrence than WHO grading and links aggressive tumors to loss of DREAM complex repression.

bioRxiv · Sep 10, 2019Cancer Biology

The Repertoire of Mutational Signatures in Human Cancer

L. Alexandrov, J. Kim, N. J. Haradhvala, M. N. Huang, A. W. T. Ng, Y. Wu, A. Boot, K. R. Covington, D. A. Gordenin, E. Bergstrom, S. M. A. Islam, N. Lopez-Bigas, L. J. Klimczak, J. R. McPherson, S. Morganella, , M. R. Stratton

The paper characterizes 49 mutational signatures in human cancer using a large dataset of somatic mutations, revealing associations with exposures and DNA repair mechanisms and identifying signatures of unknown origin.

bioRxiv · Jul 3, 2019Cancer Biology