Parasite histones mediate leak and coagulopathy in cerebral malaria
C. A. Moxon, Y. Alhamdi, J. Storm, J. Toh, J. Y. Ko, G. Murphy, T. Taylor, K. Seydel, S. Kampondeni, M. Potchen, J. O'Donnell, N. O'Regan, G. Wang, G. Garcia-Cardena, M. Molyneux, , C.-H. Toh
This study shows parasite histones contribute to coagulopathy and vascular leak in cerebral malaria, leading to brain swelling and poor outcomes.
bioRxiv · Mar 20, 2019 · PreprintMicrobiology