Author

G. Murphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Craig· 1 shared A. Gambus· 1 shared A. P. Carreca· 1 shared C. A. Moxon· 1 shared C. Ward· 1 shared C.-H. Toh· 1 shared D. Blakemore· 1 shared E. Gonzalez· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Craig

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MYBL2 regulates ATM to control replication initiation and prevent replication stress in pluripotent stem cells

D. Blakemore, R. Almaghrabi, N. Vilaplana, E. Gonzalez, M. Moya, C. Ward, G. Murphy, A. Gambus, E. Petermann, G. Stewart, P. Garcia

This study shows MYBL2 activates ATM to suppress replication stress in ESCs, with loss of MYBL2 or ATM causing replication fork slowing and increased origin firing.

bioRxiv · Jun 4, 2020Cell Biology

TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1

A. P. Carreca, V. M. Pravata, G. Murphy, H. Nagase, L. Troeberg, S. D. Scilabra

This study identifies MMP-1 as a new LRP-1 ligand and shows TIMP-3 enhances its binding to LRP-1, promoting scavenging of MMP-1.

bioRxiv · Dec 23, 2019Biochemistry

Parasite histones mediate leak and coagulopathy in cerebral malaria

C. A. Moxon, Y. Alhamdi, J. Storm, J. Toh, J. Y. Ko, G. Murphy, T. Taylor, K. Seydel, S. Kampondeni, M. Potchen, J. O'Donnell, N. O'Regan, G. Wang, G. Garcia-Cardena, M. Molyneux, , C.-H. Toh

This study shows parasite histones contribute to coagulopathy and vascular leak in cerebral malaria, leading to brain swelling and poor outcomes.

bioRxiv · Mar 20, 2019 · PreprintMicrobiology