Helicobacter pylori cancer associated CagA protein drives intestinal metaplastic transition in human gastric organoids
M. Reines, M. Soerensen, H. Berger, P. Schlaermann, M. Patel, T. F. Meyer
This study shows that Helicobacter pylori's CagA protein induces intestinal metaplasia in human gastric organoids by activating STAT3 and increasing intestinal markers.
bioRxiv · Nov 22, 2023 · PreprintCell Biology