Spinning sugars in antigen biosynthesis: a direct study of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
A. R. Cross, S. Roy, M. Vivoli Vega, M. Rejzek, S. A. Nepogodiev, M. Cliff, D. Salmon, M. N. Isupov, R. A. Field, J. L. Prior, N. J. Harmer, Glycoengineering of Veterinary Vaccines (GoVV)
This paper studies the TDP-sugar epimerases in Coxiella burnetii and Streptomyces griseus, showing they perform the RmlC 3,5 double epimerisation activity and support TDP-rhamnose biosynthesis.
bioRxiv · Oct 25, 2021 · PreprintBiochemistry