Author

M. Roca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:non-human primate· 2 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Barreiro· 2 shared A. Fernandez· 2 shared A. McDougall· 2 shared A. Prenafeta· 2 shared C. Garriga· 2 shared E. Christians· 2 shared E. Pradenas· 2 shared G. Bech-Sabat· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Barreiro

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates

A. Prenafeta, G. Bech-Sabat, S. Moros, A. Barreiro, A. Fernandez, M. Canete, M. Roca, L. Gonzalez, C. Garriga, J. Confais, M. Toussenot, H. Contamin, A. Pizzorno, M. Rosa-Calatrava, E. Pradenas, , L. Ferrer

This study evaluates the PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates, showing high antibody levels, balanced cellular immunity, and reduced viral load.

bioRxiv · Dec 13, 2022Immunology

Acquisition of the Spindle Assembly Checkpoint and its modulation by cell fate and cell size in a chordate embryo

M. Roca, L. Besnardeau, E. Christians, A. McDougall, J. Chenevert, S. Castagnetti

The paper shows that the SAC is acquired in chordate embryos during the 7th cell cycle and modulates mitotic progression based on cell fate and size.

bioRxiv · May 18, 2022Cell Biology

Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2

A. Barreiro, A. Prenafeta, G. Bech-Sabat, M. Roca, E. Perozo, R. March, L. Gonzalez-Gonzalez, L. Madrenas, J. Corominas, A. Fernandez, A. Moros, M. Molas, T. Pentinat-Pelegrin, C. Panosa, A. Moreno, , Barr

This paper evaluates a recombinant RBD fusion heterodimer vaccine in mice, showing 100% efficacy against SARS-CoV-2 variants and neutralizing antibodies.

bioRxiv · Nov 22, 2021Immunology

The spindle assembly checkpoint functions during early development in non-chordate embryos.

J. Chenevert, M. Roca, L. Besnardeau, A. Ruggiero, D. Nabi, A. McDougall, R. R. Copley, E. Christians, S. Castagnetti

The paper evaluates SAC activation in early embryos of diverse metazoan species, finding two classes of embryos with or without SAC proficiency, and suggests SAC activity is default in metazoans, silenced in chordates.

bioRxiv · Mar 19, 2019Cell Biology