Impact of glycan positioning on HIV-1 Env glycan shield density, function, and antibody recognition
Q. Wei, A. A. Harget, B. Knoppova, A. Duverger, R. Ravi, C.-H. Shen, S. K. Farney, S. Hall, R. Brown, B. F. Keele, S. L. Heath, M. S. Saag, O. Kutsch, G.-Y. Chuang, P. D. Kwong, , J. Novak
This study shows how changes in individual glycan units of HIV-1 Env affect structure, function, and antibody recognition through high-resolution glycomics and molecular dynamics.
bioRxiv · Mar 31, 2020Microbiology