Role of c-Met/β1 integrin complex in the metastatic cascade
D. Lau, H. Wadhwa, S. Sudhir, S. Jain, A. Chandra, A. Nguyen, J. Spatz, S. S. Shah, J. Cheng, M. Safaee, G. Yagnik, A. Jahangiri, M. K. Aghi
This study identifies the c-Met/β1 integrin complex as a driver of breast cancer intravasation and bone metastasis, suggesting therapeutic targeting could prevent metastases.
bioRxiv · Apr 20, 2020 · PreprintCancer Biology