SARS-CoV-2 causes severe alveolar inflammation and barrier dysfunction
S. Deinhardt-Emmer, S. Böttcher, C. Häring, L. Giebeler, A. Henke, R. Zell, F. Hornung, C. Brandt, M. Marquet, A. S. Mosig, M. W. Pletz, M. Schacke, J. Roedel, R. Heller, S. Nietzsche, , C. Ehrhardt
This study shows SARS-CoV-2 infects alveolar epithelial cells, causing inflammation and barrier dysfunction, while endothelial cells are damaged through cytokine release from infected epithelial cells.
bioRxiv · Aug 31, 2020Microbiology