MicrobiologybioRxiv
SARS-CoV-2 causes severe alveolar inflammation and barrier dysfunction
S. Deinhardt-Emmer, S. Böttcher, C. Häring…·C. Ehrhardt
This study shows SARS-CoV-2 infects alveolar epithelial cells, causing inflammation and barrier dysfunction, while endothelial cells are damaged through cytokine release from infected epithelial cells.
DOI 10.1128/jvi.00110-21