Author

M. Serafim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. O'Donoghue· 2 shared A. Kaczorowska· 1 shared A.-E. Fedoy· 1 shared B. Hurysz· 1 shared B. M. Hurysz· 1 shared C. Caffrey· 1 shared C. J. Kirk· 1 shared D. F. Trujillo· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

A. J. O'Donoghue

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Development of subunit selective substrates for Trichomonas vaginalis proteasome

P. Fajtova, B. Hurysz, Y. Miyamoto, M. Serafim, Z. Jiang, D. F. Trujillo, L. J. Liu, U. Somani, J. Almaliti, S. Myers, C. Caffrey, W. H. Gerwick, C. J. Kirk, E. Boura, L. Eckmann, A. J. O'Donoghue

The paper develops three subunit-specific fluorogenic substrates for the T. vaginalis proteasome and identifies effective inhibitor targets.

bioRxiv · Apr 5, 2023 · PreprintBiochemistry

Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system

V. Royseth, B. M. Hurysz, A. Kaczorowska, S. Dorawa, A.-E. Fedoy, H. Arsin, M. Serafim, O. Werbowy, T. Kaczorowski, R. Stokke, A. J. O'Donoghue, I. H. Steen

This study characterizes globupain, a thermostable C11 protease from an Arctic hydrothermal vent, revealing its activation mechanism, substrate preference, and thermal stability.

bioRxiv · Apr 4, 2023 · PreprintMicrobiology