Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy
L. Picchianti, V. Sanchez de Medina Hernandez, N. Zhan, N. A. T. Irwin, M. Stephani, H. Hornegger, R. Beveridge, J. Sawa-Makarska, T. Lendl, N. Grujic, S. Martens, T. A. Richards, T. Clausen, S. Ramundo, E. G. Karagoz, Y. Dagdas
The paper shows that non-canonical shuffled ATG8 interacting motifs in C53 link UFMylation and autophagy, revealing an ancestral regulatory mechanism for ER homeostasis.
bioRxiv · Apr 26, 2022Plant Biology