Design of D-amino acids SARS-CoV-2 Main protease inhibitors using the cationic peptide from rattlesnake venom as a scaffold
R. J. Eberle, I. Gering, M. Tusche, P. N. Ostermann, L. Mueller, O. Adams, H. Schaal, D. S. Olivier, M. S. Amaral, R. K. Arni, D. Willbold, M. Coronado
The paper designs D-amino acid-based inhibitors of SARS-CoV-2 3CLpro using a rattlesnake venom peptide scaffold, showing in vitro and in vivo antiviral activity.
bioRxiv · Nov 10, 2021Biochemistry