Author

M. Zoltek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Schepartz· 3 shared X. Zhang· 2 shared A. L. Vazquez-Maldonado· 1 shared A. Vazquez· 1 shared D. D. Brauer· 1 shared D. Mozumdar· 1 shared J. Giudice· 1 shared L. Lesiak· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

A. Schepartz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Requirements for efficient endosomal escape by designed mini-proteins

J. Giudice, D. D. Brauer, M. Zoltek, A. Vazquez, M. J. S. Kelly, A. Schepartz

This paper identifies the requirements for efficient endosomal escape by ZF5.3, a mini-protein, showing pH-induced unfolding and lipid-BMP interaction are critical for its function.

bioRxiv · Apr 5, 2024 · PreprintBiochemistry

Design rules for efficient endosomal escape

M. Zoltek, A. L. Vazquez-Maldonado, X. Zhang, N. Dadina, L. Lesiak, A. Schepartz

This paper identifies design rules for efficient endosomal escape by showing that protein size and thermal stability influence delivery efficiency when conjugated to ZF5.3.

bioRxiv · Nov 3, 2023 · PreprintCell Biology

Dose-dependent nuclear delivery and transcriptional repression with a cell-penetrant MeCP2

X. Zhang, M. Zoltek, D. Mozumdar, A. Schepartz

This study shows that ZF-tMeCP2, a cell-penetrant MeCP2 variant, can deliver to the nucleus and repress transcription from methylated promoters, suggesting a potential therapeutic strategy for Rett syndrome.

bioRxiv · Jun 3, 2022Biochemistry