ImmunologybioRxivPreprint
TREM1+ regulatory myeloid cells expand in steatohepatitis-HCC and associate with poor prognosis and therapeutic resistance to immune checkpoint blockade
J. Giraud, D. Chalopin, E. Ramel…·M. Saleh
This study identifies TREM1+CD163+ regulatory myeloid cells in steatohepatitis-HCC that suppress T cell function and are linked to poor prognosis and resistance to immune checkpoint therapy.