ImmunologybioRxiv
Unveiling the crucial role of type IV secretion system and motility of Helicobacter pylori in IL-1β production via NLRP3 inflammasome activation in neutrophils
A.-R. Jang, M.-J. Kang, J.-I. Shin…·J.-H. Park
This study identifies host and bacterial factors, including TLR2, NLRP3 inflammasome, type IV secretion system, and bacterial motility, essential for H. pylori-induced IL-1β production in neutrophils.
DOI 10.3389/fimmu.2020.01121