Author

María A. Pajares

Centro de Investigaciones Biológicas Margarita Salas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Dolores Pérez‐SalaiD· 2 shared Alma E. MartíneziD· 1 shared Álvaro Viedma-PoyatosiD· 1 shared Cristina Vidal-Verdú· 1 shared Elena Hernández-Gerez· 1 shared Nuria Goya‐IglesiasiD· 1 shared Patricia González-JiméneziD· 1 shared Paula Martínez-CenalmoriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Dolores Pérez‐SalaORCID

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2 papers

Recent·Most cited

Cell BiologyFree Radical Biology and MedicinePeer-reviewedMay 6, 2026

Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant

Elena Hernández-Gerez, Nuria Goya‐Iglesias, Álvaro Viedma-Poyatos…·Dolores Pérez‐Sala

This study shows that expressing the GFAP R239C mutant in astrocytes disrupts lysosomal function, acidification, and repair, contributing to proteostasis defects and neurodegeneration in Alexander disease.

1 citation

humanproteomics

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Cell BiologyScience AdvancesPeer-reviewedJun 1, 2024

Intracellular pH modulates vimentin remodeling in response to oxidants

Alma E. Martínez, Paula Martínez-Cenalmor, Patricia González-Jiménez…·Dolores Pérez‐Sala

This study shows that intracellular pH modulates vimentin remodeling by oxidants through the thiol group at C328, affecting its susceptibility to oxidative and electrophilic stress.

3 citations

humanproteomics

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