Author

Mark Rubinstein

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Anirban ChakrabortyiD· 1 shared Brian NeeloniD· 1 shared Chloe MattilaiD· 1 shared Debashis GhoshiD· 1 shared Dongjun ChungiD· 1 shared Eric Hong· 1 shared Gang XiniD· 1 shared Haitao Wen· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Anirban ChakrabortyORCID

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2 papers

Recent·Most cited

RKMR: A Rapid Kernel Machine Regression Framework for Optimal Marker Detection in Spatial Omics Data

Souvik Seal, Anirban Chakraborty, Chloe Mattila, Mark Rubinstein, Peggi M. Angel, Debashis Ghosh, Dongjun Chung, Brian Neelon

RKMR identifies predictive marker panels in spatial omics data using a scalable framework that integrates kernel modeling and spatial dependence.

bioRxiv · Sep 23, 2026 · PreprintBioinformatics

The in vivo inhibitory function of the MHC-I alpha3 domain/CD8alpha interaction

Jing Zhao, Lawrence Feng, Yang Xu, Kareem Alsbei, Jun Wang, Tiffany Zhou, Qipeng Zhan, Shiya Sun, Eric Hong, Lingbin Meng, Ning Jin, Xiaolin Cheng, Haitao Wen, Gang Xin, Mark Rubinstein, , Linghua Zheng

This study identifies the MHC-I alpha3 domain-CD8 interaction as an inhibitory pathway that restrains CD8+ T-cell activation and maintains tolerance in vivo.

bioRxiv · May 26, 2026 · PreprintImmunology