Author

Mark W Richards

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Arkadiusz Oleksy· 1 shared David Matthews· 1 shared Isabelle Vernos· 1 shared Richard Bayliss· 1 shared Selena G Burgess· 1 shared Tommaso Cavazza· 1 shared

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2016-2016 · peak 1/yr

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1 shared paperBiochemistry

Arkadiusz Oleksy

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1 paper

Recent·Most cited

BiochemistryOpen BiologyPeer-reviewedJul 1, 2016

Allosteric inhibition of Aurora-A kinase by a synthetic VNAR nanobody

Selena G Burgess, Arkadiusz Oleksy, Tommaso Cavazza…·Richard Bayliss

This paper describes the development of an allosteric inhibitor for Aurora-A kinase using a synthetic VNAR nanobody, showing it stabilizes an inactive conformation distinct from the activator TPX2.

DOI 10.1098/rsob.160089

protein structureexperimental assay

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