Author

Mary Young

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam Gordon· 1 shared Bianca Lec· 1 shared Brandon A. ThompsoniD· 1 shared Christopher B. FoxiD· 1 shared Chuyu CheniD· 1 shared Cristina Alarcon· 1 shared Erin Smithberger· 1 shared Farha NaziD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adam Gordon

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2 papers

Recent·Most cited

Enhanced immunogenicity of a Clostridioides difficile TcdB vaccine adjuvanted with a synthetic dual-TLR ligand adjuvant.

Farha Naz, Nicholas Hagspiel, Feifan Xu, Brandon A. Thompson, G. Brett Moreau, Mary Young, Joel F. Herbein, Christopher B. Fox, William A. Petri, Mayuresh M. Abhyankar

This paper evaluates a TcdB vaccine adjuvanted with a dual-TLR ligand liposome, showing complete protection against lethal CDI in mice and superior antibody and memory B cell responses compared to alum.

npj Vaccines · Feb 18, 2025Peer-reviewedImmunology

Genetic association of primary non-response to Anti-TNFα therapy in patients with Inflammatory Bowel Disease

Tanima De, Honghong Zhang, Cristina Alarcon, Bianca Lec, Juan Avitia, Erin Smithberger, Chuyu Chen, Minnie Horvath, Sara Kwan, Mary Young, Sarbani Adhikari, John Kwon, Jennifer Pacheco, Gail Pairitz Jarvik, Wei-Qi Wei, , Minoli A. Perera

This paper identifies a genetic variant associated with primary non-response to anti-TNFα therapy in IBD patients and links it to increased TNF secretion through autophagy mechanisms.

Pharmacogenetics and Genomics · Aug 12, 2021Peer-reviewedGenetic & Genomic Medicine