The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity
Jeanne Bigot, Rachel Legendre, Juliette Hamroune, Sébastien Jacques, Mathieu Le Gars, Nicolas Millet, Loïc Guillot, Harriet Corvol, C. Hennequin, J. Guitard, Jean‐Yves Coppée, Viviane Balloy, Claudia Chica
The paper identifies an epigenetic mechanism in bronchial epithelial cells that enables trained immunity through chromatin remodeling and gene expression changes following flagellin exposure.
Genes and Immunity · Sep 24, 2025Peer-reviewedGenetics