Claudia Chica

The paper identifies stress-responsive Mycobacterium tuberculosis subpopulations that influence macrophage polarization and shows targeting GroEL2 can limit inflammation.

This study uses single-cell RNA-seq to show that NK cells reprogram transcriptionally and functionally after Streptococcus pneumoniae infection, revealing new roles in bacterial immunity.

The paper identifies an epigenetic mechanism in bronchial epithelial cells that enables trained immunity through chromatin remodeling and gene expression changes following flagellin exposure.

SCHNAPPs is a Shiny-based tool for bench-scientists to analyze scRNA-seq data, offering quality control, clustering, differential expression, and visualization with reproducible reporting.

The paper identifies an epigenetic signature in Cockayne syndrome fibroblasts, showing similarities to normal aging and differences from other progeroid diseases.

ChIPflow is a pipeline for epigenomic data analysis from raw data to differential analysis, showing that statistical settings affect results depending on chromatin factor dynamics and variability.