Jeanne Bigot

This study identifies ITGB1 and MRC2 as host factors involved in bronchial epithelial cell antifungal activity through interactions with A. fumigatus lectin FleA, revealing two pathways that inhibit fungal filamentation.

This study identifies a complement-inflammasome signaling axis that drives excessive inflammation during Pseudomonas aeruginosa and Aspergillus fumigatus co-infection in cystic fibrosis patients.

The paper identifies an epigenetic mechanism in bronchial epithelial cells that enables trained immunity through chromatin remodeling and gene expression changes following flagellin exposure.

The paper investigates echinocandin resistance in Candida species, finding that increased consumption did not lead to significant resistance, but mutations in glucan synthase genes affect fitness differently across species.

The paper identifies C. africana in vaginal swabs from French Guiana using PCR and reports a new diploid sequence type.