Molecular BiologySciencePeer-reviewed
Structural Basis for eIF2B Inhibition in Integrated Stress Response
Kazuhiro Kashiwagi, Takeshi Yokoyama, Madoka Nishimoto…·Takuhiro Ito
The paper determines cryo-EM and crystal structures of eIF2B with phosphorylated and unphosphorylated eIF2 to reveal how eIF2 phosphorylation inhibits eIF2B activity.
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