Cancer BiologybioRxiv
Moonlighting Role of Meiotic SYCP1 in Breast Cancer: A Chromatin-Bound Regulator of DNA Repair, Transcription, and Drug Resistance
Urszula Lucja McClurg, Wee-Wei Tee, Owen Richard Davies…·Andrew B. Fielding
This study identifies SYCP1 as a chromatin-bound regulator in breast cancer that promotes DNA repair, transcription, and drug resistance, with clinical implications for prognosis and therapy.
DOI 10.1126/sciadv.aea2067