Author

Mengke Yang

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:imaging· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Eline Stas· 2 shared Hongbo JiaiD· 2 shared Jing LyuiD· 2 shared Simon R. SchultziD· 2 shared Yuguo TangiD· 2 shared Adrian M. IsaacsiD· 1 shared Alla MikheenkoiD· 1 shared Anny DevoyiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Eline Stas

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Author profile →

4 papers

Recent·Most cited

Ultra-wide-field, deep, adaptive two-photon microscopy

Mengke Yang, Zhen-Qiao Zhou, Song Lang, H. Z. Zheng, Shuai Chen, Tong Li, Eline Stas, Jess Yu, Long Zhang, Zhi Zhang, Volkan Uzungil, Qinying Liu, Yu Huang, Jing Lyu, Yimei Li, , Simon R. Schultz

This paper introduces a high-resolution two-photon microscopy system capable of imaging large brain regions with cellular resolution.

Light Science & Applications · Apr 13, 2026Peer-reviewedNeuroscience

Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer's disease

Eline Stas, Mengke Yang, Simon R. Schultz, Mary Ann Go

This study uses three-photon imaging to track vascular degeneration and amyloid plaque changes in a mouse model of Alzheimer's disease over four weeks.

Journal of Biomedical Optics · Jan 2, 2026Peer-reviewedNeuroscience

PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons

Carmelo Milioto, Mireia Carcolé, Ashling Giblin, Rachel Coneys, Olivia N. Attrebi, Mhoriam Ahmed, Sam Harris, Byung Il Lee, Mengke Yang, Raja Sekhar Nirujogi, Daniel Biggs, Sally E. Salomonsson, Matteo Zanovello, Paula De Oliveira, Eszter Katona, , Adrian M. Isaacs

The paper generates C9orf72 DPR knock-in mice and identifies an extracellular matrix signature in C9ALS/FTD that is conserved across species and protected by TGF-β1 and COL6A1.

bioRxiv · Jul 17, 2023 · PreprintNeuroscience

MATRIEX Imaging: Multi-Area Two-photon Real-time In-vivo Explorer

Mengke Yang, Zhenqiao Zhou, Jianxiong Zhang, Shanshan Jia, Tong Li, Jiangheng Guan, Xiang Liao, Bing Leng, Jing Lyu, Kuan Zhang, Min Li, Yan Jun Gong, Zhiming Zhu, Junan Yan, Yi Zhou, , Hongbo Jia

The paper introduces a method for multi-area two-photon imaging in awake mice, enabling simultaneous single-cell resolution imaging across different brain regions.

Light Science & Applications · Nov 28, 2019Peer-reviewedNeuroscience