Synthetic BiologyACS Synthetic BiologyPeer-reviewed
An orthogonal and pH-tunable sensor-selector for muconic acid biosynthesis in yeast
Tim Snoek, David Romero-Suárez, Jie Zhang…·Jay D. Keasling
The paper develops a synthetic selection system in yeast to enrich for high-producing muconic acid variants by coupling production to cell fitness through a pH-tunable sensor-selector.
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