Author

Michael Chen

Washington University in St. LouisPrimary ORCID profile (0000-0002-0819-233X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Michael CheniD1 paper · University of California San Diego

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Yifan DaiiD· 2 shared Aaron NagieliD· 1 shared Alberto Javier EspayiD· 1 shared Aleksandra V. SergeevaiD· 1 shared András MajoriD· 1 shared Anthony A. HymaniD· 1 shared Asima Nayak· 1 shared Axel A. EkmaniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Yifan DaiORCID

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Author profile →

3 papers

Recent·Most cited

Redox surveillance of stress granules prevents TDP-43 aggregation

Xiao Yan, Silja Zedlitz, Xuemeng Chen, Yi-Cheng Tsai, Yuefeng Ma, Michael Chen, Linge Li, David Kuster, Jik Nijssen, Aleksandra V. Sergeeva, Yiyang Chen, Casey Welch, Wen Yu, Zongru Li, Marco Messina, , Anthony A. Hyman

This study shows that redox surveillance in stress granules prevents TDP-43 aggregation by maintaining a controlled redox environment.

bioRxiv · Oct 19, 2026 · PreprintCell Biology

Reverse engineering Lewy bodies suggests alpha-synuclein pathology as condensatopathy

Roberto Sansevrino, Александр Коробейников, Jianhua Chen, Christian Hoffmann, Hugo Le Roy, Kiersten M. Ruff, András Major, Asima Nayak, Paula Brosius, Axel A. Ekman, Shujin He, Michael Chen, Joshua Jackson, Gerard Aguilar Pérez, Han Wang, , Dragomir Milovanović

The paper shows that alpha-synuclein phase separation can form Lewy body-like structures without pre-existing seeds, suggesting a new mechanism for neurodegeneration.

bioRxiv · Oct 15, 2026 · PreprintNeuroscience

mGluR6 coordinates cone terminal targeting and synaptic layer assembly during human retinal development

Leila Bahmani, Patricia Galvan, Hirad Hosseini, Jinlun Bai, Sumitha Prameela Bharathan, Michael Chen, Kayla Stepanian, Matthew Edward Thornton, Brendan H. Grubbs, Aaron Nagiel

This study identifies mGluR6's role in human retinal development by showing its transient expression in cone photoreceptors and its requirement for proper synaptic layer assembly.

bioRxiv · Apr 27, 2026 · PreprintNeuroscience