Author

David Kuster

Max Planck Institute of Molecular Cell Biology and GeneticsORCID 0000-0002-8157-9223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Aleksandra V. SergeevaiD· 2 shared Anthony A. HymaniD· 2 shared Jik NijsseniD· 2 shared Karina Pombo GarcíaiD· 2 shared Simon AlbertiiD· 2 shared Alf HonigmanniD· 1 shared Anh M. Ly· 1 shared Azamat RizuaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

Aleksandra V. SergeevaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 19, 2026

Redox surveillance of stress granules prevents TDP-43 aggregation

Xiao Yan, Silja Zedlitz, Xuemeng Chen…·Anthony A. Hyman

This study shows that redox surveillance in stress granules prevents TDP-43 aggregation by maintaining a controlled redox environment.

DOI 10.64898/2026.10.16.759411

humanexperimental assay

𝕏 PostBluesky

Cell BiologyCellPeer-reviewedMay 23, 2025

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

Xiao Yan, David Kuster, Priyesh Mohanty…·Anthony A. Hyman

This study shows that TDP-43 aggregation in stress granules requires up-concentration and oxidative stress, leading to intra-condensate demixing and pathological aggregates.

183 citationstop 1%

humanproteomics

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