Author

Yiyang Chen

Ministry of Agriculture and Rural Affairs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aleksandra V. SergeevaiD· 1 shared Anthony A. HymaniD· 1 shared B. X. Li· 1 shared Baochao FaniD· 1 shared Boshui Yuan· 1 shared Casey Welch· 1 shared David KusteriD· 1 shared Dewen TongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Aleksandra V. SergeevaORCID

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2 papers

Recent·Most cited

Redox surveillance of stress granules prevents TDP-43 aggregation

Xiao Yan, Silja Zedlitz, Xuemeng Chen, Yi-Cheng Tsai, Yuefeng Ma, Michael Chen, Linge Li, David Kuster, Jik Nijssen, Aleksandra V. Sergeeva, Yiyang Chen, Casey Welch, Wen Yu, Zongru Li, Marco Messina, , Anthony A. Hyman

This study shows that redox surveillance in stress granules prevents TDP-43 aggregation by maintaining a controlled redox environment.

bioRxiv · Oct 19, 2026 · PreprintCell Biology

Coronavirus envelope protein drives iron sensing disorder by hijacking the TAp73-FDXR axis

Mingjun Zhu, Leyu Hu, Xingwei Fu, Boshui Yuan, Guiwen Guan, Lu Han, Zesheng Rong, Ru Tian, Gen Li, Muzi Du, Yan Ma, Ning Xu, Haixin Liu, Haolun Tian, Xinhuan Yin, , Dewen Tong

This study identifies how the coronavirus envelope protein disrupts the TAp73-FDXR axis to cause iron overload, leading to iron deficiency perception and tissue damage, and presents a therapeutic molecule to counteract this effect.

bioRxiv · Mar 25, 2026 · PreprintMicrobiology