Author

Michael Jonathan

Joint Research Center for Human Retrovirus Infection, Kumamoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:proteomics· 1

Frequent Co-Authors

Akatsuki SaitoiD· 2 shared Ryo Shimizu· 2 shared Terumasa IkedaiD· 2 shared Akifumi Takaori‐KondoiD· 1 shared Alfredo A. HinayiD· 1 shared Anon H. KosakaiD· 1 shared Arnon PlianchaisukiD· 1 shared Ayaka SakamotoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Akatsuki SaitoORCID

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3 papers

Recent·Most cited

APOBEC3 antagonism fully explains HIV-1 Vif essentiality under interferon and differentiation conditions

Ryo Shimizu, Michael Jonathan, Hiromi Terasawa, Akatsuki Saito, Kazuaki Monde, Terumasa Ikeda

This study shows that HIV-1 Vif's essential role in infectivity under interferon and differentiation conditions is fully explained by its antagonism of APOBEC3 proteins, not other targets.

bioRxiv · Apr 17, 2026 · PreprintMicrobiology

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

Shuhei Tsujino, Masumi Tsuda, Sayaka Deguchi, Jumpei Ito, Taha Y. Taha, Hesham Nasser, Lei Wang, Julia Rosecrans, Rigel Suzuki, Saori Suzuki, Kumiko Yoshimatsu, Mélanie Ott, Terumasa Ikeda, Kei Sato, Kazuo Takayama, , Miki Kawano

This study identifies the non-spike R204P mutation in the SARS-CoV-2 Omicron XEC variant as a driver of increased inflammation and pathogenicity through NF-κB activation.

Nature Communications · Dec 14, 2025Peer-reviewedMicrobiology

The Integrator complex cleaves nascent mRNAs to attenuate transcription

Deirdre C. Tatomer, Nathan D. Elrod, Dongming Liang, Mei‐Sheng Xiao, Jeffrey Z. Jiang, Michael Jonathan, Kai-Lieh Huang, Eric J. Wagner, Sara R. Cherry, Jeremy E. Wilusz

The paper identifies the Integrator complex as a regulator of transcription by cleaving nascent mRNAs, revealing its role in attenuating gene expression during copper stress.

bioRxiv · Aug 28, 2019Molecular Biology