Cancer BiologybioRxivPreprint
Harnessing the Embryo Antitumor Factor NEPN for Broad-Spectrum Cancer Immunotherapy via Dual Modulation of Tumor Progression and Immune Suppression
Tzu‐Pei Chang, Yu-Jui Ho, Mohamad Hamieh…·Kitai Kim
This study identifies NEPN as a tumor-suppressive embryonic factor that enhances cancer immunotherapy by modulating TGFβ1 signaling and immune responses in both non-solid and solid tumors.
DOI 10.1101/2025.09.29.679137