Author

Mitchell Kesler

University of Calgary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:zebrafish· 1

Frequent Co-Authors

Deborah Marie KurraschiD· 2 shared Jong M. RhoiD· 2 shared Alexandra K. WalliD· 1 shared Antis G. GeorgeiD· 1 shared Bianca R. VillaiD· 1 shared Cassandra D. KinchiD· 1 shared Cristiane Lucia Rodriguez de la Hoz· 1 shared Cristie Grazziotin NoschangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Deborah Marie KurraschORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Inhibition of phosphodiesterase 4B as a novel therapeutic strategy for the treatment of refractory epilepsy

Cassandra D. Kinch, Mitchell Kesler, Deepika Dogra, Kyle Morin, Kingsley Ibhazehiebo, Cristie Grazziotin Noschang, Jong M. Rho, Deborah Marie Kurrasch

SN-2000, a novel PDE4B inhibitor, reduces seizure activity and shows psychiatric-neutral and pro-cognitive properties in preclinical models.

bioRxiv · May 13, 2025 · PreprintNeuroscience

Sudden unexpected death in epilepsy is prevented by blocking postictal hypoxia

Antis G. George, Jordan S. Farrell, Roberto Colangeli, Alexandra K. Wall, Renaud C. Gom, Mitchell Kesler, Cristiane Lucia Rodriguez de la Hoz, Bianca R. Villa, Tefani Perera, Jong M. Rho, Deborah Marie Kurrasch, G. Campbell Teskey

This study shows that blocking postictal hypoxia prevents SUDEP in mice by preventing seizure-induced vasoconstriction.

Neuropharmacology · Mar 21, 2023Peer-reviewedNeuroscience