Author

Deepika Dogra

University of Calgary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 5

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Approach:experimental assay· 4 Organism:zebrafish· 4 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Deborah Marie KurraschiD· 4 shared Cezar GavriloviciiD· 3 shared Kingsley Ibhazehiebo· 3 shared Jong M. RhoiD· 2 shared Anneke Korver· 1 shared Brooke BurrisiD· 1 shared Cassandra D. KinchiD· 1 shared Cristiane Lucia Rodriguez de la Hoz· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersNeuroscience

Deborah Marie KurraschORCID

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5 papers

Recent·Most cited

SCN1A haploinsufficiency disrupts neural progenitor networks and accelerates neurogenesis in human Dravet syndrome forebrain assembloids

Deepika Dogra, Harmony Fong, Sinan Zhang, Takuma Sumi, Nicole L. Rosin, Nicolás Collao, Marissa Gordon, Anneke Korver, Cezar Gavrilovici, Duncan Noble, Segundo Jose Guzman, Leili Rohani, Derrick E. Rancourt, Jeff A. Biernaskie, Julia Jacobs-LeVan, , Deborah Marie Kurrasch

This study shows that SCN1A haploinsufficiency disrupts neural progenitor networks and accelerates neurogenesis in human Dravet syndrome forebrain assembloids, leading to altered corticogenesis and circuit hyperexcitability.

bioRxiv · Oct 16, 2026 · PreprintNeuroscience

Inhibition of phosphodiesterase 4B as a novel therapeutic strategy for the treatment of refractory epilepsy

Cassandra D. Kinch, Mitchell Kesler, Deepika Dogra, Kyle Morin, Kingsley Ibhazehiebo, Cristie Grazziotin Noschang, Jong M. Rho, Deborah Marie Kurrasch

SN-2000, a novel PDE4B inhibitor, reduces seizure activity and shows psychiatric-neutral and pro-cognitive properties in preclinical models.

bioRxiv · May 13, 2025 · PreprintNeuroscience

Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling

Deepika Dogra, Van Anh Phan, Cezar Gavrilovici, Nadia DiMarzo, Kingsley Ibhazehiebo, Deborah Marie Kurrasch

This study shows that loss-of-function mutations in zebrafish slc13a5 cause epilepsy-like phenotypes, which are rescued by blocking NMDA receptor signaling.

bioRxiv · Jan 15, 2024 · PreprintNeuroscience

kcna1a mutant zebrafish as a model of episodic ataxia type 1 and epilepsy

Deepika Dogra, Paola L. Meza Santoscoy, Renata Rehak, Cristiane Lucia Rodriguez de la Hoz, Cezar Gavrilovici, Kingsley Ibhazehiebo, Jong M. Rho, Deborah Marie Kurrasch

This paper uses zebrafish kcna1a-/- mutants to model EA1 and epilepsy, showing ataxia-like behaviors, brain hyperexcitability, and responsiveness to carbamazepine.

bioRxiv · Sep 28, 2022 · PreprintNeuroscience

Myostatin is a negative regulator of adult neurogenesis in zebrafish

Vishnu Muraleedharan Saraswathy, Lili Zhou, Brooke Burris, Deepika Dogra, Sven Reischauer, Mayssa H. Mokalled

This study shows myostatin b inhibits neurogenesis in zebrafish spinal cord, and its loss improves functional recovery without affecting axonal or glial bridging.

bioRxiv · Aug 18, 2021 · PreprintNeuroscience