Author
Altius Institute for Biomedical Sciences
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
CJ Kelly, Janessa Wagandi, Danny Quaranta…·Nikolay Burnaevskiy
This study identifies transcriptional overmaturation as a key trajectory in naive CD4 T cell aging, showing aging-related changes mirror normal maturation processes.
Wouter R. A. Meuleman, Alexander Muratov, Eric Rynes…·John A. Stamatoyannopoulos
The paper creates high-precision maps of DNase I hypersensitive sites across 733 human biosamples and develops a regulatory vocabulary to annotate regulatory DNA, concentrating disease-associated signals.
Jeff D. Vierstra, John E. Lazar, Richard S. Sandstrom…·John A. Stamatoyannopoulos
The paper maps transcription factor footprints across 243 human cell and tissue types, revealing their structure, function, and relationship to genetic variation and disease.
Charles E. Breeze, John E. Lazar, Tim R. Mercer…·John A. Stamatoyannopoulos
The paper creates a mouse regulatory DNA atlas by mapping DNase I hypersensitive sites across development and shows dynamic changes in regulatory elements and transcription factor activity.
Jesse R. Dixon, Jie Xu, Vishnu Dileep…·Feng Yue
This paper presents an integrative framework to detect structural variants in cancer genomes using multiple methods and finds that non-coding structural variation significantly impacts genome function in cancer cells.