Author

Murphy McDermott

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Abdou Rachid ThiamiD· 1 shared Apoorva Bhapkar· 1 shared Fabienne FoufelleiD· 1 shared Jennica Träger· 1 shared Mehdi ZouiouichiD· 1 shared Mohyeddine OmraneiD· 1 shared Sami Kchir· 1 shared Sonny YdeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Abdou Rachid ThiamORCID

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1 paper

Recent·Most cited

ER cholesteryl ester phase separation underlies switch-like cholesterol sensing

Mehdi Zouiouich, Apoorva Bhapkar, Jennica Träger, Murphy McDermott, Sonny Yde, Sami Kchir, Fabienne Foufelle, Mohyeddine Omrane, Abdou Rachid Thiam

The paper identifies cholesterol esterification as a mechanism that creates switch-like regulation of the INSIG/SCAP/SREBP2 pathway through ER membrane phase transitions.

bioRxiv · Aug 10, 2026 · PreprintCell Biology