ADAPs intrinsically disordered region is an actin sponge regulating T cell motility
N. Dadwal, J. Degen, J. Sticht, T. Hilal, T. Wegner, P. Reichardt, R. Lyck, M. Hons, M. Abadier, C. Mix, B. Kuropka, H. Stephanowitz, F. Liu, B. Schraven, C. Wuelfing, , C. Freund
This study identifies ADAP's intrinsically disordered region as an actin sponge that regulates T cell motility by promoting actin polymerization and bundling.
bioRxiv · Dec 14, 2021 · PreprintBiochemistry