Author

T. Wegner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Freund· 2 shared S. Kliche· 2 shared A. E. Zucchetti· 1 shared A. L. Linard Matos· 1 shared A. Zheng· 1 shared B. Bruegger· 1 shared B. Kuropka· 1 shared B. Schraven· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

C. Freund

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3 papers

Recent·Most cited

ADAPs intrinsically disordered region is an actin sponge regulating T cell motility

N. Dadwal, J. Degen, J. Sticht, T. Hilal, T. Wegner, P. Reichardt, R. Lyck, M. Hons, M. Abadier, C. Mix, B. Kuropka, H. Stephanowitz, F. Liu, B. Schraven, C. Wuelfing, , C. Freund

This study identifies ADAP's intrinsically disordered region as an actin sponge that regulates T cell motility by promoting actin polymerization and bundling.

bioRxiv · Dec 14, 2021 · PreprintBiochemistry

Leukocyte adhesion is governed by endolysosomal two pore channel 2 (TPC2)

J. Goretzko, N. Heitzig, K. Thomas, E. K. Krogsaeter, J. Nass, A. L. Linard Matos, T. Wegner, S. Schloer, V. Gerke, J. Rossaint, F. Glorius, F. Bracher, C. M. Grimm, U. Rescher

The paper shows that TPC2 regulates endothelial cell surface P-selectin by controlling CD63 transfer from endosomes to Weibel-Palade bodies, affecting leukocyte recruitment during inflammation.

bioRxiv · Sep 28, 2021 · PreprintImmunology

Dynamic Palmitoylation Events Following T-Cell Receptor Signaling

E. Morrison, T. Wegner, A. E. Zucchetti, M. Alvaro-Benito, A. Zheng, S. Kliche, E. Krause, B. Bruegger, C. Hivroz, C. Freund

The paper identifies dynamic palmitoylation events in T-cells following TCR signaling, showing DHHC18 palmitoylates VAMP7 at Cys183, affecting its Golgi retention.

bioRxiv · Nov 5, 2019Biochemistry