MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria
Y.-J. Park, N. Dodantenna, T.-H. Kim, H.-S. Lee, Y.-S. Yoo, E.-S. Lee, J.-H. Lee, M.-H. Kwon, H. C. Kang, J.-S. Lee, H. Cho
This study identifies MARCH5-dependent NLRP3 ubiquitination as essential for NEK7 mitochondrial docking during inflammasome assembly.
bioRxiv · Jan 12, 2023 · PreprintImmunology