Author

N. Federman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:organoid / primary culture· 2

Frequent Co-Authors

A. Al Shihabi· 2 shared A. Davarifar· 2 shared A. Soragni· 2 shared F. Hornicek· 2 shared H. T. L. Nguyen· 2 shared J. Yanagawa· 2 shared N. Bernthal· 2 shared N. Tavanaie· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Al Shihabi

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2 papers

Recent·Most cited

The landscape of drug sensitivity and resistance in sarcoma

A. Al Shihabi, P. J. Tebon, H. T. L. Nguyen, J. Chantharasamee, S. Sartini, A. Davarifar, A. Y. Jensen, M. Diaz-Infante, H. Cox, A. Enrique-Gonzalez, S. Swearingen, N. Tavanaie, S. Dry, A. Singh, B. Chmielowski, , A. Soragni

This study uses patient-derived tumor organoids to identify drug sensitivity and resistance patterns in sarcoma, finding actionable treatment regimens for 59% of tested specimens.

bioRxiv · May 25, 2023Cancer Biology

Personalized chordoma organoids for drug discovery studies

A. Al Shihabi, A. Davarifar, H. T. L. Nguyen, N. Tavanaie, S. D. Nelson, J. Yanagawa, N. Federman, N. Bernthal, F. Hornicek, A. Soragni

This study establishes patient-derived chordoma organoids to identify effective targeted therapies, finding PI3K/mTOR, EGFR, and JAK2/STAT3 inhibitors as promising candidates.

bioRxiv · May 27, 2021Cancer Biology