Analysis of Drosophila and mouse mutants reveals that Peroxidasin is required for tissue mechanics and full viability
K. E. Peebles, K. S. LaFever, P. S. Page-McCaw, S. Colon, D. Wang, A. M. Stricker, N. Ferrell, G. Bhave, A. Page-McCaw
This study shows that Peroxidasin is essential for tissue mechanics and viability in Drosophila and mouse mutants, with homozygous escapers showing reduced stiffness and partial Col4 crosslinking.
bioRxiv · Jul 19, 2023Cell Biology