Septin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2
G. Russo, N. Hümpfer, N. Jaensch, S. Restel, C. Schmied, F. Heyd, M. Lehmann, V. Haucke, H. Ewers, M. Krauss
This study identifies septin-associated PIPKIγ splice variants as essential for midbody organization by generating PI(4,5)P2 required for centralspindlin recruitment and septin-microtubule association.
bioRxiv · Feb 22, 2024 · PreprintCell Biology