Author

N. L. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Pankow· 2 shared B. Murrell· 2 shared C. Kim· 2 shared D. J. Sheward· 2 shared E. Urgard· 2 shared G. M. McInerney· 2 shared J. M. Coquet· 2 shared L. Hanke· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Pankow

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralising SARS-CoV-2 nanobodies

L. Hanke, D. J. Sheward, A. Pankow, L. Perez Vidakovics, V. Karl, C. Kim, E. Urgard, N. L. Smith, J. Astorga-Wells, S. Ekström, J. M. Coquet, G. M. McInerney, B. Murrell

This study identifies potent cross-neutralizing SARS-CoV-2 nanobodies from an alpaca immune repertoire using phage display and epitope mapping.

bioRxiv · Jul 25, 2021Immunology

Driving potent neutralization of a SARS-CoV-2 Variant of Concern with a heterotypic boost

D. J. Sheward, M. Mandolesi, E. Urgard, C. Kim, L. Hanke, L. Perez Vidakovics, A. Pankow, N. L. Smith, X. Castro Dopico, G. M. McInerney, J. M. Coquet, G. Karlsson Hedestam, B. Murrell

A single dose of a VOC-derived RBD protein boost enhances potent neutralizing antibodies against both Wu-Hu-1 and the VOC in previously vaccinated rhesus macaques.

bioRxiv · Apr 3, 2021 · PreprintImmunology

A Conserved TCRβ signature dominates a highly polyclonal T-cell expansion during the acute phase of a murine malaria infection

N. L. Smith, W. Nahrendorf, C. Sutherland, J. P. Mooney, J. Thompson, P. J. Spence, G. J. M. Cowan

The paper identifies a conserved TCRβ signature dominated by TRBV3 gene usage in a highly polyclonal T-cell expansion during the acute phase of a murine malaria infection.

bioRxiv · Jul 27, 2020Immunology

Adaptive periodicity in the infectivity of malaria gametocytes to mosquitoes

P. Schneider, S. S. C. Rund, N. L. Smith, K. F. Prior, A. J. O'Donnell, S. E. Reece

The paper shows that malaria gametocytes are more infective to mosquitoes at night, despite lower blood density, and that daytime feeding increases sporozoite burdens due to higher mosquito susceptibility.

bioRxiv · Apr 5, 2018Microbiology