Author

N. Linden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

a. Karner· 1 shared A. R. Harders· 1 shared A. R. Teixeira· 1 shared A. S. Huang· 1 shared C. Bittar· 1 shared C. Dirscherl· 1 shared C. Uetrecht· 1 shared F. Muecksch· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

a. Karner

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Author profile →

2 papers

Recent·Most cited

Transcription of HIV-1 at sites of intact latent provirus integration

A. R. Teixeira, C. Bittar, G. S. Silva Santos, T. Y. Oliveira, A. S. Huang, N. Linden, I. A. T. M. Ferreira, T. Murdza, F. Muecksch, R. B. Jones, M. Caskey, M. Jankovic, M. C. Nussenzweig

This study examines transcription of HIV-1 at sites of intact latent provirus integration in T cells, finding that latent proviral promoters are significantly less active than in productively infected cells and have minimal impact on neighboring gene expression.

bioRxiv · Apr 26, 2024Immunology

Dissociation of β2m from MHC Class I Triggers Formation of Noncovalent, Transient Heavy Chain Dimers

C. Dirscherl, S. Loechte, Z. Hein, J.-D. Kopicki, A. R. Harders, N. Linden, a. Karner, j. preiner, J. Weghuber, M. Garcia-Alai, C. Uetrecht, M. Zacharias, J. Piehler, P. Lanzerstorfer, S. Springer

This study investigates the formation of non-covalent MHC-I heavy chain dimers after dissociation of β2m and peptide, revealing a dimerization interface mediated by the 3 domain.

bioRxiv · Jul 2, 2021Cell Biology