Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice
B. Vanderkruk, N. Maeshima, D. J. Pasula, M. An, C. L. McDonald, F. C. Lynn, D. S. Luciani, B. Hoffman
This study shows that H3K4me3 is essential for maintaining beta cell function in adult mice by supporting gene expression for insulin biosynthesis and glucose responsiveness.
bioRxiv · Jan 28, 2021Cell Biology