Sensory Neurons Innervate Peripheral Lymph Nodes and Locally Regulate Gene Expression in Postsynaptic Endothelium, Stromal Cells, and Innate Leukocytes
S. Huang, C. G. K. Ziegler, J. Austin, N. Mannoun, M. Vukovic, J. Ordovas-Montanes, A. K. Shalek, U. H. von Andrian
The paper identifies sensory neurons innervating lymph nodes and shows they modulate gene expression in endothelium, stromal cells, and innate leukocytes through direct communication.
bioRxiv · Nov 11, 2019 · PreprintImmunology