J. Ordovas-Montanes

This paper uses an intestine-on-a-chip model to study NL63 coronavirus infection effects on the human intestine and tests antiviral treatments.

This study analyzes nasopharyngeal samples from COVID-19 patients and healthy controls to identify how SARS-CoV-2 infection affects respiratory epithelial cells and immune responses, finding impaired local intrinsic immunity in severe cases.

This study identifies cyclin D3 as essential for inertial cell cycling in dark zone germinal center B cells, enabling clonal expansion and linking it to potential lymphoproliferative disorders.

The paper identifies cellular and temporal factors associated with bacterial control in tuberculosis granulomas using multimodal data.

The paper uses SIVS and scRNA-seq to analyze T cell infiltration and residency in the GI tract during aGVHD, identifying genes associated with tissue invasiveness and TRM programming.

This paper develops a high-throughput organoid screening method to identify agents that alter intestinal epithelial composition, finding Xpo1 inhibitors increase Paneth cell abundance.

The paper identifies sensory neurons innervating lymph nodes and shows they modulate gene expression in endothelium, stromal cells, and innate leukocytes through direct communication.

This study profiles single-cell RNA-seq data from human respiratory tissues to show reduced epithelial diversity and altered basal progenitor states in type 2 immunity-driven diseases.